Nature Communications (May 2019)
A strongly adhesive hemostatic hydrogel for the repair of arterial and heart bleeds
- Yi Hong,
- Feifei Zhou,
- Yujie Hua,
- Xianzhu Zhang,
- Chengyao Ni,
- Dihao Pan,
- Yiqing Zhang,
- Deming Jiang,
- Long Yang,
- Qiuning Lin,
- Yiwei Zou,
- Dongsheng Yu,
- David E. Arnot,
- Xiaohui Zou,
- Linyong Zhu,
- Shufang Zhang,
- Hongwei Ouyang
Affiliations
- Yi Hong
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Feifei Zhou
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Yujie Hua
- Optogenetics and Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, School of Chemistry and Molecular Engineering, East China University of Science and Technology
- Xianzhu Zhang
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Chengyao Ni
- Department of Cardiothoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
- Dihao Pan
- Department of Cardiothoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine
- Yiqing Zhang
- Optogenetics and Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, School of Chemistry and Molecular Engineering, East China University of Science and Technology
- Deming Jiang
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Long Yang
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Qiuning Lin
- Optogenetics and Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, School of Chemistry and Molecular Engineering, East China University of Science and Technology
- Yiwei Zou
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Dongsheng Yu
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- David E. Arnot
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Xiaohui Zou
- Clinical Research Center, The First Affiliated Hospital, Zhejiang University School of Medicine
- Linyong Zhu
- Optogenetics and Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, School of Chemistry and Molecular Engineering, East China University of Science and Technology
- Shufang Zhang
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- Hongwei Ouyang
- Department of Orthopaedic Surgery, Second Affiliated Hospital and Zhejiang University-University of Edinburgh Institute and School of Basic Medicine, Zhejiang University School of Medicine
- DOI
- https://doi.org/10.1038/s41467-019-10004-7
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 11
Abstract
Uncontrollable bleeding is a major problem in surgery and after trauma. Here the authors design a photo-reactive adhesive that mimics the composition of connective tissue and is able to stop high pressure bleeding within half a minute.
