Viruses (Feb 2022)

Academ Virus, a Novel Hantavirus in the Siberian Mole (<i>Talpa altaica</i>) from Russia

  • Liudmila N. Yashina,
  • Victor V. Panov,
  • Sergey A. Abramov,
  • Natalia A. Smetannikova,
  • Ekaterina M. Luchnikova,
  • Tamara A. Dupal,
  • Anton V. Krivopalov,
  • Satoru Arai,
  • Richard Yanagihara

DOI
https://doi.org/10.3390/v14020309
Journal volume & issue
Vol. 14, no. 2
p. 309

Abstract

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To date, six hantavirus species have been detected in moles (family Talpidae). In this report, we describe Academ virus (ACDV), a novel hantavirus harbored by the Siberian mole (Talpa altaica) in Western Siberia. Genetic analysis of the complete S-, M-, and partial L-genomic segments showed that ACDV shared a common evolutionary origin with Bruges virus, previously identified in the European mole (Talpa europaea), and is distantly related to other mole-borne hantaviruses. Co-evolution and local adaptation of genetic variants of hantaviruses and their hosts, with possible reassortment events, might have shaped the evolutionary history of ACDV.

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