Российский кардиологический журнал (Apr 2009)

BLOOD LIPID AND NON-LIPID BIOMARKERS IN NOVOSIBIRSK MEN WITH CORONARY ATHEROSCLEROSIS

  • Yu. I. Ragino,
  • A. M. Chernyavsky,
  • A. V. Tikhonov,
  • S. Yu. Tsymbal,
  • Ya. V. Polonskaya,
  • E. V. Semaeva,
  • M. V. Ivanova,
  • M. I. Voevoda

Journal volume & issue
Vol. 0, no. 2
pp. 31 – 35

Abstract

Read online

Blood lipid (total cholesterol (CH), triglycerides, low and high-density lipoprotein CH (LDL-CH, HDL-CH), lipoprotein (a)) and non-lipid (high-sensitive C-reactive protein (hsCRP), homocysteine, interleukins (IL) beta, 6, and 8, tumor necrosis factor (TNF), metalloproteinase (MP) 3 and 9) were measured in 96 Novosibirsk men, aged 42–70 years, with angiography-confirmed coronary atherosclerosis and Functional Class II-IV stable effort angina, but without acute coronary syndrome. More than 70% of the patients demonstrated an increase in blood levels of total CH, LDL-CH, hsCRP, homocysteine, IL-6, IL-8, and especially MP-9 (elevated in 100% of the men examined).

Keywords