The mechanisms of blood system regulation under myelosuppressive influences

Abstract

As a result of many years experiments by studying of blood system function under radiation and cytostatic myelosuppressions it has been shown, that observing changes and mechanisms, underlying in their basis, are unspecific and of the same type. However the specific reaction of blood system depends on the nature of acting irritant. The hemopoiesis recovery dynamics, together with direct suppressed effect of toxic agents on hemopoietic cells, in many respects, is determined by character of regulatory systems, and first of all separate elements, forming hemopoiesis – inducing microenvironment.

Keywords

• система крови
• микроокружение
• регуляция
• цитостатики
• миелосупрессия