Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma

Harvind S. Chahal; Yuan Lin; Katherine J. Ransohoff; David A. Hinds; Wenting Wu; Hong-Ji Dai; Abrar A. Qureshi; Wen-Qing Li; Peter Kraft; Jean Y. Tang; Jiali Han; Kavita Y. Sarin

doi:10.1038/ncomms12048

Nature Communications (Jul 2016)

Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma

Harvind S. Chahal,
Yuan Lin,
Katherine J. Ransohoff,
David A. Hinds,
Wenting Wu,
Hong-Ji Dai,
Abrar A. Qureshi,
Wen-Qing Li,
Peter Kraft,
Jean Y. Tang,
Jiali Han,
Kavita Y. Sarin

Affiliations

Harvind S. Chahal: Department of Dermatology, Stanford University School of Medicine
Yuan Lin: Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University
Katherine J. Ransohoff: Department of Dermatology, Stanford University School of Medicine
David A. Hinds: 23andMe Inc.
Wenting Wu: Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University
Hong-Ji Dai: Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University
Abrar A. Qureshi: Department of Dermatology, Warren Alpert Medical School, Brown University
Wen-Qing Li: Department of Dermatology, Warren Alpert Medical School, Brown University
Peter Kraft: Department of Epidemiology, Harvard T.H. Chan School of Public Health
Jean Y. Tang: Department of Dermatology, Stanford University School of Medicine
Jiali Han: Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University
Kavita Y. Sarin: Department of Dermatology, Stanford University School of Medicine

DOI: https://doi.org/10.1038/ncomms12048
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 8

Abstract

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Cutaneous squamous cell carcinoma is the second most common type of skin cancer. In this genome-wide association study, which includes over 7,000 cases, the authors identify 4 new susceptibility loci for this cancer and also provide independent replication of 9 previously reported susceptibility loci.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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