ETIOLOGY, PATHOGENESIS, CLINICAL PRESENTATION, DIAGNOSTICSAND TREATMENT OF THE PRIMARY HYPERPARATHYROIDISM

Abstract

Primary hyperparathyroidism (PHPT) is a common endocrine disorder that affects bones, urinary tract, cardiovascular system, gastrointestinal tract, and another organs and tissues. The most cases of PHPT are mild forms and those patients have nonspecific symptoms, which require careful diagnostic considerations and choice of treatment. There is not enough data about prevalence of PHPT, especially it's mild forms, in Russian Federation, and future epidemiological research needs to be done. Present literature review includes information about etiology, pathogenesis, clinical findings, diagnostic and differential diagnostic, indication for surgery and medical treatment of PHPT. The review is based on data of studies from the different countries and few studies from Endocrine science center.

Keywords

• первичный гиперпаратиреоз
• эпидемиология
• клиническая картина
• показания к хирургическому лечению
• медикаментозная терапия