Melatonin protects against cadmium-induced oxidative stress via mitochondrial STAT3 signaling in human prostate stromal cells

Affiliations

Moonjung Hyun: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Hyejin Kim: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Jehein Kim: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Juhong Lee: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Ho Jeong Lee: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Laxmi Rathor: Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida
Jeremy Meier: Division of Hematology, UNC School of Medicine, University of North Carolina
Andrew Larner: Department of Biochemistry and Molecular Biology, Virginia Commonwealth University
Seon Min Lee: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Yeongyu Moon: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Jungil Choi: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology
Sung Min Han: Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida
Jeong-Doo Heo: Gyeongnam Biohealth Research Center, Gyeongnam Branch Institute, Korea Institute of Toxicology

Abstract

Melatonin protects against cadmium through regulation of mitoSTAT3 and reduction of ROS damage in human prostate stromal cells.