Disseminated Histoplasmosis in a Patient with Aplastic Anemia

Abstract

Histoplasmosis is a systemic mycosis which has a worldwide distribution.Though common in immunocompromised patients, disseminated histoplasmosis has rarely been reported in patients with aplastic anemia. We report here a case of very severe aplastic anemia who developed disseminated histoplasmosis in the form of hepatic involvement, which proved fatal due to lack of cell mediated immunity.

Keywords

• Histoplasmosis
• Aplastic anemia
• Amphotericin