Monitoring adverse drug reactions to Thai herbal remedies (Ya Satree) in Thailand: Observational study

Abstract

Healthcare systems worldwide mainly require spontaneous reporting on identified adverse drug reactions (ADRs) to prevent future ADRs. This study aimed to investigate ADRs that may occur from the use of Ya satree and to determine unwanted incident information for selecting new drugs to be included in the National List of Essential Medicines in Thailand. A prospective study was conducted among patients from 13 government hospitals. The 1100 participants received Ya satree for 4 consecutive weeks. The data were collected by interviews and with a structured questionnaire. The results showed that 1044 cases were completely followed-up. 78 cases had progression of ADRs assessments. From Naranjo’ Algorithm scores, 32 participants showed probable scores and had ADR symptoms such as dizziness and headache. 42 participants showed possible scores and had ADR symptoms such as increased appetite and dizziness. However, all ADRs were non-serious may be related to the use of Ya satree.

Keywords

• monitoring
• adverse drug reaction (adr)
• thai herbal remedies (ya satree)