Probiotics in the management of respiratory diseases: ways of interaction and therapeutic perspectives

Abstract

Today, the composition of the gut microbiota has been studied in sufficient detail. Increasing number of studies show that the respiratory tract, both the upper and lower respiratory tract, have their own microbiota. The article presents the main today’s data about the species diversity of microorganisms in the respiratory and gastrointestinal tracts, describes the role of a healthy microbiota in providing local and general immunity. The authors specify the role of probiotic strains of microorganisms and their effect on various parts of the immune response and present the data of studies on the effect of probiotic products on the immunological resistance of humans, especially the respiratory tract with high viral load. Restoration of a healthy microbiota in the human tract using probiotic products administered through the gastrointestinal tract can reduce the risk and severity of manifestation of the respiratory infections.

Keywords

• microbiota
• respiratory tract
• gastrointestinal tract
• inborn immunity
• commensals
• probiotics
• lactobacilli
• prebiotics
• synbiotics