Establishment of a human induced pluripotent stem cell line (CSUASOi010-A) by reprogramming peripheral blood mononuclear cells of a type 2 diabetic mellitus patient

Chengcheng Ding; Feng Tan; Yalan Zhou; Chunwen Duan; Jianing Gu; Zekai Cui; Zhongping Chen; Shibo Tang; Jiansu Chen

Stem Cell Research (Aug 2022)

Establishment of a human induced pluripotent stem cell line (CSUASOi010-A) by reprogramming peripheral blood mononuclear cells of a type 2 diabetic mellitus patient

Chengcheng Ding,
Feng Tan,
Yalan Zhou,
Chunwen Duan,
Jianing Gu,
Zekai Cui,
Zhongping Chen,
Shibo Tang,
Jiansu Chen

Affiliations

Chengcheng Ding: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Feng Tan: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Yalan Zhou: Affiliated Hospital of Jining Medical College, China
Chunwen Duan: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Jianing Gu: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Zekai Cui: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China
Zhongping Chen: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Changsha Aier Eye Hospital, #388 Furong Middle Road, Changsha, Hunan 410015, China
Shibo Tang: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, China; Corresponding authors at: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China.
Jiansu Chen: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Aier School of Ophthalmology, Central South University, P.R.C., 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China; Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China; Institute of Ophthalmology, Medical College, Jinan University, Guangzhou 510632, China; Corresponding authors at: Aier Eye Institute, 18th Floor, the New Century Building, #198 Furong Middle Road, Changsha, Hunan 410015, China.

Journal volume & issue: Vol. 63
p. 102851

Abstract

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Type 2 diabetes mellitus (T2DM) is a major caused by insulin resistance with a relative deficiency in insulin secretion. Statistically, T2DM accounts for 90% of diabetes cases worldwide. We report the patient-specific human induced pluripotent stem cell line (iPSC) CSUASOi010-A by using Peripheral blood mononuclear cells (PBMCs) of a 62-year-old female from Type 2 diabetes mellitus (T2DM). Patient blood-derived cells were reprogrammed using the Sendai virus.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

About the journal