Nature Communications (Mar 2020)
Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring
- Peter J. Vuillermin,
- Martin O’Hely,
- Fiona Collier,
- Katrina J. Allen,
- Mimi L. K. Tang,
- Leonard C. Harrison,
- John B. Carlin,
- Richard Saffery,
- Sarath Ranganathan,
- Peter D. Sly,
- Lawrence Gray,
- John Molloy,
- Angela Pezic,
- Michael Conlon,
- David Topping,
- Karen Nelson,
- Charles R. Mackay,
- Laurence Macia,
- Jennifer Koplin,
- Samantha L. Dawson,
- Margarita Moreno-Betancur,
- Anne-Louise Ponsonby,
- the J. Craig Venter Institute,
- the BIS Investigator Group
Affiliations
- Peter J. Vuillermin
- Deakin University, School of Medicine
- Martin O’Hely
- Deakin University, School of Medicine
- Fiona Collier
- Deakin University, School of Medicine
- Katrina J. Allen
- The Murdoch Children’s Research Institute
- Mimi L. K. Tang
- The Murdoch Children’s Research Institute
- Leonard C. Harrison
- The University of Melbourne
- John B. Carlin
- The Murdoch Children’s Research Institute
- Richard Saffery
- The Murdoch Children’s Research Institute
- Sarath Ranganathan
- The Murdoch Children’s Research Institute
- Peter D. Sly
- The Murdoch Children’s Research Institute
- Lawrence Gray
- Deakin University, School of Medicine
- John Molloy
- Deakin University, School of Medicine
- Angela Pezic
- The Murdoch Children’s Research Institute
- Michael Conlon
- Commonwealth Science and Industrial Research Organisation
- David Topping
- Commonwealth Science and Industrial Research Organisation
- Karen Nelson
- J. Craig Venter Institute
- Charles R. Mackay
- Monash University
- Laurence Macia
- University of Sydney, Charles Perkins Centre
- Jennifer Koplin
- The Murdoch Children’s Research Institute
- Samantha L. Dawson
- Deakin University, School of Medicine
- Margarita Moreno-Betancur
- The Murdoch Children’s Research Institute
- Anne-Louise Ponsonby
- The Murdoch Children’s Research Institute
- the J. Craig Venter Institute
- the BIS Investigator Group
- DOI
- https://doi.org/10.1038/s41467-020-14552-1
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 7
Abstract
Incidence of food allergy in westernized populations is associated with low abundance of Prevotella. Here, the authors analyse the microbiome of a mother-infant prebirth cohort and find that maternal carriage, but not infant carriage, of P. copri during pregnancy predicts the absence of food allergy in the offspring.