Case Reports in Hematology (Jan 2021)

A Rare Cause of Acquired Factor X Deficiency in an 87-Year-Old Female

  • Ayrton Bangolo,
  • Trupti Waykole,
  • Bilal Niazi,
  • Chandini Sajja,
  • Mahabuba Akhter,
  • Bhavna Gupta,
  • Sameh Elias

DOI
https://doi.org/10.1155/2021/1138329
Journal volume & issue
Vol. 2021

Abstract

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Factor X deficiency is a rare coagulopathy that can be inherited or acquired. Acquired factor X deficiency has been associated with plasma cell dyscrasias, amyloids, and use of vitamin K antagonists. Of plasma cell dyscrasias, most cases in the literature have been associated with multiple myeloma with or without concomitant AL amyloidosis. Here, we present a rare case of acquired isolated factor X deficiency in an elderly patient with immunoglobulin A (Ig A) monoclonal gammopathy of undetermined significance (MGUS). Herein, we highlight a rare cause of acquired factor X deficiency, and we hope to contribute to the growing literature of plasma cell dyscrasias associated with factor X deficiency.