Bangladesh Journal of Pharmacology (Nov 2014)

Antimicrobial activity of ethanolic extracts of Justicia neesii

  • Sridhar Nimmakayala,
  • Suguna Lakshmi Duggirala,
  • Goverdhan Puchchakayala

Journal volume & issue
Vol. 9, no. 4

Abstract

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Agar well diffusion method was used to evaluate the antimicrobial potential of Justicia neesii extract. The maximum activity index (AI) values are observed against Klebsiella pneumonia (1.208) and low AI value for Streptococcus faecalis (0.963) compared to other bacterial species. The maximum AI values are observed against Saccharomyces cerevisiae (1.147) and low AI value for Fusarium axisporum (0.986) compared to other fungal species. The MIC and MBC/MFC values indicated the bacteriostatic/ fungistatic nature of the extract and also having good correlation with the zone of inhibition values. The total activity values indicated that J. neesii extract can show antimicrobial activity even at higher dilutions, except for Gram negative bacteria.

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