Nature Communications (May 2021)

Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit

  • Timothy V. Pyrkov,
  • Konstantin Avchaciov,
  • Andrei E. Tarkhov,
  • Leonid I. Menshikov,
  • Andrei V. Gudkov,
  • Peter O. Fedichev

DOI
https://doi.org/10.1038/s41467-021-23014-1
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

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Aging is associated with an increased risk of chronic diseases and functional decline. Here, the authors investigate the fluctuations of physiological indices along aging trajectories and observed a characteristic decrease in the organism state recovery rate.