Clinical Case Reports (Aug 2023)

Invasive breast carcinoma of no special type with medullary pattern: A case report at a tertiary facility in Tanzania

  • Alex Mremi,
  • Marianne Gnanamuttupulle,
  • Shilanaiman Hilary Ntundu,
  • Oliver Henke,
  • Kondo Chilonga,
  • David Msuya

DOI
https://doi.org/10.1002/ccr3.7844
Journal volume & issue
Vol. 11, no. 8
pp. n/a – n/a

Abstract

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Key Clinical Message Describes a rare form of invasive breast cancer of no special type. Not a distinct morphological subtype. Characterized by dense lymphoid infiltrate, syncytial growth, pushing borders, and cells with high‐grade nuclei. Clinically aggressive but carries a better prognosis than other more frequent invasive breast carcinomas. Abstract Invasive breast carcinoma of no special type with medullary pattern (BCNST‐MP) is a rare form of breast tumor, accounting for less than 5% of all invasive breast carcinomas. Its diagnosis is based on histologic criteria. Historically, this tumor was known as medullary carcinoma. Poor morphological reproducibility led to re‐classification. Despite having an aggressive biological behavior, these tumors usually carry a better prognosis compared with other more frequent forms of invasive breast carcinomas. Herein, we present a case of BCNST‐MP in a 58‐year‐old African female, successfully treated in our institution through chemo‐radiation, hormonal therapy and surgery.

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