Translational Neuroscience (May 2020)
Neuroprotective mechanisms of erythropoietin in a rat stroke model
- Juenemann Martin,
- Braun Tobias,
- Schleicher Nadine,
- Yeniguen Mesut,
- Schramm Patrick,
- Gerriets Tibo,
- Ritschel Nouha,
- Bachmann Georg,
- Obert Martin,
- Schoenburg Markus,
- Kaps Manfred,
- Tschernatsch Marlene
Affiliations
- Juenemann Martin
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Braun Tobias
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Schleicher Nadine
- Heart & Brain Research Group, Justus-Liebig-University Giessen and Kerckhoff Clinic, Benekestrasse 2-8, 61231, Bad Nauheim, Germany
- Yeniguen Mesut
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Schramm Patrick
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Gerriets Tibo
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Ritschel Nouha
- Max-Planck-Institute for Heart and Lung Research, Ludwigstraße 43, 61231, Bad Nauheim, Germany
- Bachmann Georg
- Department of Radiology, Kerckhoff Clinic, 61231, Bad Nauheim, Germany
- Obert Martin
- Department of Radiology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Schoenburg Markus
- Department of Cardiac Surgery, Kerckhoff Clinic, 61231, Bad Nauheim, Germany
- Kaps Manfred
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- Tschernatsch Marlene
- Department of Neurology, Justus-Liebig-University Giessen, Klinikstrasse 33, 35392, Giessen, Germany
- DOI
- https://doi.org/10.1515/tnsci-2020-0008
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 48 – 59
Abstract
This study was designed to investigate the indirect neuroprotective properties of recombinant human erythropoietin (rhEPO) pretreatment in a rat model of transient middle cerebral artery occlusion (MCAO).
Keywords
- neuroprotection
- rat
- recombinant human erythropoietin
- transient focal cerebral ischemia
- vascular disorders
- craniectomy
