Footprints of Stress in Vitiligo: Association of the 5-HTR2C rs6318 Variant

Abstract

Vitiligo is a chronic, progressive autoimmune dermatological disease, and stress is known to have an impact on the development of vitiligo. However, the effect of the serotonin pathway and its impact have not been clearly explained for disease progression. Thus, this study aimed to clarify the stress induced serotonin receptor 5-HTR2C rs6318 variant and its association with vitiligo pathogenesis.

Keywords

• case-control study
• polymorphism
• stress
• vitiligo
• 5-htr2c rs6318