METAnnotatorX2: a Comprehensive Tool for Deep and Shallow Metagenomic Data Set Analyses

Christian Milani; Gabriele Andrea Lugli; Federico Fontana; Leonardo Mancabelli; Giulia Alessandri; Giulia Longhi; Rosaria Anzalone; Alice Viappiani; Francesca Turroni; Douwe van Sinderen; Marco Ventura

doi:10.1128/mSystems.00583-21

mSystems (Jun 2021)

METAnnotatorX2: a Comprehensive Tool for Deep and Shallow Metagenomic Data Set Analyses

Christian Milani,
Gabriele Andrea Lugli,
Federico Fontana,
Leonardo Mancabelli,
Giulia Alessandri,
Giulia Longhi,
Rosaria Anzalone,
Alice Viappiani,
Francesca Turroni,
Douwe van Sinderen,
Marco Ventura

Affiliations

Christian Milani: ORCiD; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Gabriele Andrea Lugli: Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Federico Fontana: Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Leonardo Mancabelli: Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Giulia Alessandri: Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Giulia Longhi: Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Rosaria Anzalone: GenProbio srl, Parma, Italy
Alice Viappiani: GenProbio srl, Parma, Italy
Francesca Turroni: ORCiD; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy
Douwe van Sinderen: ORCiD; APC Microbiome Ireland and School of Microbiology, Bioscience Institute, National University of Ireland, Cork, Ireland
Marco Ventura: ORCiD; Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy

DOI: https://doi.org/10.1128/mSystems.00583-21
Journal volume & issue: Vol. 6, no. 3

Abstract

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We developed a novel tool, i.e., METAnnotatorX2, that includes a number of new advanced features for analysis of deep and shallow metagenomic data sets and is accompanied by (regularly updated) customized databases for archaea, bacteria, fungi, protists, and viruses. Both software and databases were developed so as to maximize sensitivity and specificity while including support for shallow metagenomic data sets.

Published in mSystems

ISSN: 2379-5077 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msystems

About the journal