Detection of Enteric Viruses in Children under Five Years of Age before and after Rotavirus Vaccine Introduction in Manhiça District, Southern Mozambique, 2008–2019

Abstract

Enteric viruses are the leading cause of diarrhoea in children p = 0.006) and LSD (25/268, 9.3% vs. 9/430, 2.1%, p p p = 0.002); and sapovirus in MSD (7.1% vs. 1.4%, p = 0.047) and controls (21/475, 4.4% vs. 51/2380, 2.1%, p = 0.004). Norovirus GII, adenovirus 40/41, astrovirus, and sapovirus detection increased in MSD and LSD cases after rotavirus vaccine introduction, supporting the need for continued molecular surveillance for the implementation of appropriate control and prevention measures.

Keywords

• enteric viruses
• diarrhoea
• rotavirus vaccine
• children
• Mozambique