Emerging Infectious Diseases (Apr 2019)
Combination of Clindamycin and Azithromycin as Alternative Treatment for Toxoplasma gondii Encephalitis
Abstract
Current standard therapies for toxoplasmic encephalitis often cause severe adverse events. A 57-year-old HIV-positive man in Japan who had toxoplasmic encephalitis but was intolerant to trimethoprim/sulfamethoxazole, pyrimethamine, sulfadiazine, and atovaquone was successfully treated with the combination of clindamycin and azithromycin. This drug combination can be an alternative treatment for this condition.
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