Advances in metal-organic framework-derived single-atom catalysts for biomedicine

Li Qiu; Yingxi Lin; Jun Song Chen; Hong Luo; Rui Wu

Nano Materials Science (Aug 2024)

Advances in metal-organic framework-derived single-atom catalysts for biomedicine

Li Qiu,
Yingxi Lin,
Jun Song Chen,
Hong Luo,
Rui Wu

Affiliations

Li Qiu: Department of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu 610041, China; Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Sichuan University, Chengdu, 611731, China
Yingxi Lin: School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, 611731, China
Jun Song Chen: School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, 611731, China; Interdisciplinary Materials Research Center, Institute for Advanced Study, Chengdu University, Chengdu, 610106, China
Hong Luo: Department of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu 610041, China; Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Sichuan University, Chengdu, 611731, China; Corresponding author. Department of Ultrasound, West China Second University Hospital, Sichuan University, Chengdu, China.
Rui Wu: School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, 611731, China; Corresponding author. School of Materials and Energy, University of Electronic Science and Technology of China, Chengdu, 611731, China.

Journal volume & issue: Vol. 6, no. 4
pp. 396 – 412

Abstract

Read online

As a alternative for natural enzymes, nanozymes has shown enzyme-like activity and selectivity in the field of various kinds of biomedical application, which has attracted considerable research interest. Recently, single-atom catalysts (SACs) have been extensively studied due to their similar active centers, coordination environment and better stability to natural enzymes. Metal-organic frameworks (MOFs) have been demonstrated as highly promising precursors for the synthesis of various types of SACs. MOF-derived SACs can not only significantly enhance the catalytic activity, but also improve the selectivity of nanozymes due to tunable coordination environment and structure, thereby receiving widespread attention in biomedicine. This review provided an overview of the preparation strategies for MOF-derived SACs, and then detailed the latest research progress of the SACs in the biomedical field for cancer, antibacterial, antioxidation and biosensors. Finally, the challenges and potential future opportunities of MOF-derived SACs in biomedical applications are proposed.

Published in Nano Materials Science

ISSN: 2589-9651 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology: Engineering (General). Civil engineering (General)
Website: https://www.keaipublishing.com/en/journals/nano-materials-science/

About the journal

Abstract

Keywords