Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis

Hristos Karakizlis; Christian Nahrgang; Kevin Strecker; Jiangping Chen; Mostafa Aly; Heiko Slanina; Christian G. Schüttler; Isla Esso; Martin Wolter; Darina Todorova; Sönke Jessen; Andrea Adamik; Claudio Ronco; Werner Seeger; Rolf Weimer; Martina Sester; Horst-Walter Birk; Faeq Husain-Syed

Data in Brief (Jun 2022)

Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis

Hristos Karakizlis,
Christian Nahrgang,
Kevin Strecker,
Jiangping Chen,
Mostafa Aly,
Heiko Slanina,
Christian G. Schüttler,
Isla Esso,
Martin Wolter,
Darina Todorova,
Sönke Jessen,
Andrea Adamik,
Claudio Ronco,
Werner Seeger,
Rolf Weimer,
Martina Sester,
Horst-Walter Birk,
Faeq Husain-Syed

Affiliations

Hristos Karakizlis: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany; Corresponding authors.
Christian Nahrgang: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Kevin Strecker: AID GmbH, Ebinger Straße 4, Strassberg 72479, Germany
Jiangping Chen: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Mostafa Aly: Transplantation Immunology, Institute of Immunology, University Hospital Heidelberg, Im Neuenheimer Feld 305, Heidelberg 69120, Germany; Nephrology Unit, Internal Medicine Department, Assiut University, Governorate 71515, Assiut, Egypt
Heiko Slanina: Institute of Medical Virology, Justus-Liebig-University Giessen, Schubertstraße 81, Giessen 35392, Germany
Christian G. Schüttler: Institute of Medical Virology, Justus-Liebig-University Giessen, Schubertstraße 81, Giessen 35392, Germany
Isla Esso: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Martin Wolter: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Darina Todorova: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Sönke Jessen: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Andrea Adamik: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Claudio Ronco: Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Via Rodolfi, Vicenza 37–36100, Italy; Department of Medicine (DIMED), Università di Padova, Via Giustiniani, Padua 2–35128, Italy
Werner Seeger: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany; Member of the German Center for Lung Research (DZL), Universities of Giessen and Marburg Lung Center (UGMLC), Klinikstraße 33, Giessen 35392, Germany; Department of Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Ludwigstraße 43, Bad Nauheim 61231, Germany
Rolf Weimer: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Martina Sester: Department of Transplant and Infection Immunology, Saarland University, Kirrberger Straße, Homburg 66421, Germany
Horst-Walter Birk: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany
Faeq Husain-Syed: Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Klinikstraße 33, Giessen 35392, Germany; Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Via Rodolfi, Vicenza 37–36100, Italy; Corresponding authors.

Journal volume & issue: Vol. 42
p. 108271

Abstract

Read online

Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been explicitly tested in this population due to their common exclusion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-γ and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a complete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a history of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durability of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

About the journal

Abstract

Keywords