Predictive value of U-wave inversion combined with fragmented QRS on electrocardiogram for prognosis of patients with acute coronary syndrome after percutaneous coronary intervention

Abstract

Objective To investigate the value of U-wave inversion combined with fragmented QRS (fQRS) on electrocardiogram in predicting the prognosis after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). Methods A total of 123 patients with ACS admitted to The Third People’s Hospital of Henan Province from October 2017 to September 2019 were included. All the patients underwent PCI after electrocardiogram examination, followed by 3 months follow-up. The percentages of U-wave inversion, fQRS, and a poor prognosis were analyzed to determine the predictive value of U-wave inversion combined with fQRS for post-PCI outcome in patients with ACS. Results Among the 123 patients with ACS, the percentages of U-wave inversion, fQRS, and a poor prognosis were 39.84%, 33.33%, and 23.58%, respectively. The patients with a poor outcome showed significantly higher percentages of U-wave inversion and fQRS than those with a good outcome (χ2=20.547,26.080,P<0.05). U-wave inversion plus fQRS showed significantly higher specificity, accuracy, and area under the curve in predicting a poor prognosis following PCI in patients with ACS, as compared with U-wave inversion and fQRS alone (χ2=3.291-11.132,Z=3.543,4.861,P<0.05). Conclusion Patients with ACS have a high risk of a poor prognosis after PCI, which could be well predicted using U-wave inversion in combination with fQRS.

Keywords

• electrocardiography|acute coronary syndrome|u-wave inversion|fragmented qrs complexes|percutaneous coronary intervention|prognosis