Nature Communications (Dec 2016)

Atomic structure of the innexin-6 gap junction channel determined by cryo-EM

  • Atsunori Oshima,
  • Kazutoshi Tani,
  • Yoshinori Fujiyoshi

DOI
https://doi.org/10.1038/ncomms13681
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

Read online

Gap junctions have critical roles in maintaining homeostasis in multicellular organisms. Here the authors present cryo-EM structures of the C. elegansinnexin-6 gap junction channel, revealing high structural similarity to human connexin 26 despite a different oligomeric number and lack of sequence similarity.