Assessment of the expediency of drugs prescriptions to patients with peptic ulcer disease in clinical practice

Abstract

Aim. Assessment of the frequency of medication prescriptions to patients with peptic ulcer disease at the Manhyia District Hospital of the Health Service of the Republic of Ghana in the city of Kumasi and determining the degree of compliance of prescribed drugs with the documents regulating the provision of medical care in the country. Material and Methods. Assessment of pharmacotherapy of patients with peptic ulcer disease was performed using clinical and economic methods: the frequency analysis and the "formal" VEN-analysis. Results and Discussion. Using the "formal" VEN-analysis, it was determined that the majority of the prescribed medications are recommended for use in the pharmacotherapy of the main (peptic ulcer disease) and concomitant diseases registered in the studied patients by the treatment standards of Ghana, and are present on the Ghana Essential Medicines List (80.00% and 83.33%, respectively). Based on the results of frequency analysis, it was found that the medications presented in these documents were prescribed in most cases (93.28% and 93.83%, respectively). Conclusions. The main directions of pharmacotherapy of patients with peptic ulcer disease at the Manhyia District Hospital of the Health Service of the Republic of Ghana in the city of Kumasi correspond the current treatment standards of Ghana for peptic ulcer disease and concomitant diseases. The prescriptions of medications recommended by treatment standards and included in the Ghana Essential Medicines List constitute the vast majority of medical prescriptions. However, the use of a significant number of secondary medications in this hospital, features of the reimbursement of pharmacotherapy of diseases by the National Insurance Company of Ghana, and the policy of the Health Service of the Republic of Ghana on the availability of all vital medications for the treatment of diseases on the Ghana Essential Medicines List indicate the need for optimization of pharmacotherapy of patients with peptic ulcer in this hospital in accordance with the above documents regulating pharmacotherapy of diseases.

Keywords

• peptic ulcer disease, clinical and economical analysis, ven-analysis, frequency analysis