Case Reports in Oncology (Mar 2022)

Acute Exacerbation of Tracheal Obstruction and Severe Respiratory Failure after a Single Dose of 2-Gy Irradiation for Squamous Cell Lung Carcinoma: A Case Report

  • Keita Kawakado,
  • Takamasa Hotta,
  • Jin Sakamoto,
  • Mika Horie,
  • Misato Kobayashi,
  • Takae Okuno,
  • Yoshihiro Amano,
  • Megumi Hamaguchi,
  • Yukari Tsubata,
  • Noriaki Kurimoto,
  • Takeshi Isobe

DOI
https://doi.org/10.1159/000523941
Journal volume & issue
Vol. 15, no. 1
pp. 356 – 361

Abstract

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The patient, a 62-year-old woman, complained chiefly of cough. We planned chemoradiotherapy for squamous nonsmall cell lung cancer. A single dose of 2-Gy irradiation and no anticancer agent administration exacerbated the airway stenosis with severe respiratory failure. Urgent tracheal intubation was performed, and a tracheal stent was implanted under extracorporeal membrane oxygenation (ECMO). Because her performance status (PS) worsened from 1 to 2, we administered radiotherapy. The tumor size decreased. There was no recurrence for the next 3 months, and her PS improved to 1. Emergency tracheal intubation and tracheal stent placement under ECMO can be effective for exacerbated airway obstruction after radiotherapy.

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