Проблемы особо опасных инфекций (Apr 2012)

Development of DNA-Biochip for Identification of Influenza A Virus Subtypes

  • A. N. Shikov,
  • E. I. Sergeeva,
  • O. K. Demina,
  • V. A. Ternovoy,
  • V. V. Ryabinin,
  • E. V. Kostina,
  • E. M. Malkova,
  • A. N. Sinyakov,
  • A. P. Agaphonov

DOI
https://doi.org/10.21055/0370-1069-2012-2(112)-89-93
Journal volume & issue
Vol. 0, no. 2(112)
pp. 89 – 93

Abstract

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Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase subtypes N1,N2 of influenza virus. This microchip was successfully tested on the strains of A/H5N1 highly pathogenic avian influenza virus, A/H1N1(2009) pandemic influenza virus, A/H1N1 and A/H3N2 seasonal influenza viruses.

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