Nature Communications (Oct 2018)

Hidden hearing loss selectively impairs neural adaptation to loud sound environments

  • Warren Michael Henry Bakay,
  • Lucy Anne Anderson,
  • Jose Alberto Garcia-Lazaro,
  • David McAlpine,
  • Roland Schaette

DOI
https://doi.org/10.1038/s41467-018-06777-y
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 11

Abstract

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Hidden hearing loss (HHL) arises through subtle damage to the synapses of hair cells in the inner ear before audiograms reveal hearing threshold shifts. Here, the authors report that HHL in a mouse model disrupts the neural encoding of loud sound environments in the central auditory system.