Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim‑1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation

• Basem Mansour,
• Yomna A. Salem,
• Khaled M. Attallah,
• O. A. El-kawy,
• Ismail T. Ibrahim,
• Naglaa I. Abdel-Aziz

Affiliations

Basem Mansour

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Dakahlia, Egypt

Yomna A. Salem

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University − Kantara Branch, Ismailia, Egypt

Khaled M. Attallah

Labeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, Egypt

O. A. El-kawy

Labeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, Egypt

Ismail T. Ibrahim

Labeled Compound Department, Hot Lab Center, Egyptian Atomic Energy Authority, Cairo, Egypt

Naglaa I. Abdel-Aziz

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Dakahlia, Egypt