Subcutaneous scalp nodule as the presenting symptom of systemic light-chain amyloidosis

Abstract

We present a case of subcutaneous nodular amyloidosis mimicking a pilar cyst. Further evaluation led to the diagnosis of malignant systemic light-chain amyloidosis. The epidemiology and histopathological features of light-chain amyloidosis with cutaneous involvement are reviewed, as well as current recommendations for initial evaluation.

Keywords

• nodular amyloidosis
• systemic AL amyloidosis
• pilar cyst
• subcutaneous nodule