Research and Reports in Urology (Sep 2020)

Trends in the Treatment Outcomes and Features of Cryptorchidism in Boys: A Single-Institute Experience

  • Hori S,
  • Aoki K,
  • Nishimura N,
  • Morizawa Y,
  • Gotoh D,
  • Fukui S,
  • Nakai Y,
  • Miyake M,
  • Torimoto K,
  • Fujimoto K

Journal volume & issue
Vol. Volume 12
pp. 373 – 381

Abstract

Read online

Shunta Hori, Katsuya Aoki, Nobutaka Nishimura, Yosuke Morizawa, Daisuke Gotoh, Shinji Fukui, Yasushi Nakai, Makito Miyake, Kazumasa Torimoto, Kiyohide Fujimoto Department of Urology, Nara Medical University, Kashihara, Nara 634-8522, JapanCorrespondence: Kiyohide FujimotoDepartment of Urology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, JapanTel +81-744-22-3051Fax +81-744-22-9282Email [email protected]: Cryptorchidism is one of the most common congenital abnormalities in pediatric urology, and orchiopexy is performed for the prevention of testicular damage and malignant transformation. We examined the distribution and outcomes of cryptorchidism under a single investigator at our institute.Patients and Methods: This retrospective study included 283 boys diagnosed with cryptorchidism at our institute. Cryptorchidism was diagnosed based on the medical history and physical examination findings. Boys without spontaneous resolution after 6 months of age were indicated for orchiopexy. We investigated the 12-year trend in the distribution and outcomes of cryptorchidism at the institute.Results: The mean age at diagnosis, gestational age, and birth weight were 2 years, 37 weeks, and 2740 g, respectively. A total of 170 boys underwent orchiopexy under 2 years of age, and 136 boys underwent orchiopexy under the age of 1 year, while 62 boys underwent orchiopexy over the age of 3 years. Abnormalities of the epididymis and disclosure of the processus vaginalis were observed in 44 (25%) and 72 boys (41%), respectively. Comparison of boys with or without hypospadias showed that the age at orchiopexy was higher in boys with hypospadias than in those without hypospadias (P=0.028). In addition, boys without hypospadias had a higher rate of abnormality of the epidermis than those with hypospadias (P=0.024).Conclusion: Our findings suggest that most boys with cryptorchidism are treated under the age of 2 years and the incidence of epididymal abnormality is relatively high, especially in boys with hypospadias. An understanding of the natural features of cryptorchidism could lead to better management and outcomes. Further research is warranted to develop an appropriate treatment timeline in boys with cryptorchidism.Keywords: cryptorchidism, hypospadias, orchiopexy, pediatrics, spontaneous resolution

Keywords