Acta Médica Portuguesa (May 2022)

The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report

  • Joana Barradas Lopes,
  • Moises Labrador-Horrilo,
  • Borja Bartolomé,
  • Leonor Cunha

DOI
https://doi.org/10.20344/amp.15483
Journal volume & issue
Vol. 35, no. 5

Abstract

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Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.

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