Synchronous Presentation of Chronic Myeloid Leukemia with Carcinoma Penis: A Rare Presentation

Abstract

We report here a case of 52-year-old male presenting with penile ulcer. On evaluation, he was diagnosed to have Carcinoma penis with concurrent CML in chronic phase. Clinical examination showed pallor, bilateral inguinal lymphadenopathy, bilateral pitting pedal oedema and hepatosplenomegaly. He was diagnosed to have chronic myeloid leukemia based on peripheral smear examination showing raised counts with shift to left and fluorescence in situ hydridisation (FISH) showing t (9:22). The ilio-inguinal block dissection specimen showed inguinal metastasis of squamous cell carcinoma (SCC). This case is being presented here in view of the rarity in combination of CML with another malignancy.

Keywords

• chronic myeloid leukemia- chronic phase (cml-cp)
• fluorescence in situ hybridization (fish)
• squamous cell carcinoma (scc)