Extensively Drug-Resistant Shigella flexneri 2a, California, USA, 2022

Abstract

In Los Angeles, California, USA, persistent, refractory shigellosis was diagnosed in an immunocompetent man who has sex with men. Whole-genome sequencing augmented phenotypic antimicrobial susceptibility testing to comprehensively profile bacterial drug resistance and appropriately guide therapy and clear the infection.

Keywords

• Shigella
• extensively drug resistant
• XDR
• whole-genome sequencing
• WGS
• next-generation sequencing