Quantifying the local adaptive landscape of a nascent bacterial community

Joao A. Ascensao; Kelly M. Wetmore; Benjamin H. Good; Adam P. Arkin; Oskar Hallatschek

doi:10.1038/s41467-022-35677-5

Nature Communications (Jan 2023)

Quantifying the local adaptive landscape of a nascent bacterial community

Joao A. Ascensao,
Kelly M. Wetmore,
Benjamin H. Good,
Adam P. Arkin,
Oskar Hallatschek

Affiliations

Joao A. Ascensao: Department of Bioengineering, University of California, Berkeley
Kelly M. Wetmore: Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory
Benjamin H. Good: Department of Applied Physics, Stanford University
Adam P. Arkin: Department of Bioengineering, University of California, Berkeley
Oskar Hallatschek: Department of Physics, University of California, Berkeley

DOI: https://doi.org/10.1038/s41467-022-35677-5
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 19

Abstract

Read online

Fitness landscapes largely shape the dynamics of evolution, but it is unclear how they shift upon ecological diversification. By engineering genome-wide knockout libraries of a nascent bacterial community, Ascensao et al. show how ecological and epistatic patterns combine to shape adaptive landscapes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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