Nature Communications (Sep 2021)
Genomic sequencing of SARS-CoV-2 in Rwanda reveals the importance of incoming travelers on lineage diversity
- Yvan Butera,
- Enatha Mukantwari,
- Maria Artesi,
- Jeanne d’arc Umuringa,
- Áine Niamh O’Toole,
- Verity Hill,
- Stefan Rooke,
- Samuel Leandro Hong,
- Simon Dellicour,
- Onesphore Majyambere,
- Sebastien Bontems,
- Bouchra Boujemla,
- Josh Quick,
- Paola Cristina Resende,
- Nick Loman,
- Esperance Umumararungu,
- Alice Kabanda,
- Marylin Milumbu Murindahabi,
- Patrick Tuyisenge,
- Misbah Gashegu,
- Jean Paul Rwabihama,
- Reuben Sindayiheba,
- Djordje Gikic,
- Jacob Souopgui,
- Wilfred Ndifon,
- Robert Rutayisire,
- Swaibu Gatare,
- Tharcisse Mpunga,
- Daniel Ngamije,
- Vincent Bours,
- Andrew Rambaut,
- Sabin Nsanzimana,
- Guy Baele,
- Keith Durkin,
- Leon Mutesa,
- Nadine Rujeni
Affiliations
- Yvan Butera
- Center for Human Genetics, College of Medicine and Health Sciences, University of Rwanda
- Enatha Mukantwari
- National Reference Laboratory, Rwanda Biomedical Center
- Maria Artesi
- Laboratory of Human Genetics, GIGA Research Institute
- Jeanne d’arc Umuringa
- National Reference Laboratory, Rwanda Biomedical Center
- Áine Niamh O’Toole
- Institute of Evolutionary Biology, University of Edinburgh
- Verity Hill
- Institute of Evolutionary Biology, University of Edinburgh
- Stefan Rooke
- Institute of Evolutionary Biology, University of Edinburgh
- Samuel Leandro Hong
- Department of Microbiology, Immunology and Transplantation, Rega Institute KU Leuven
- Simon Dellicour
- Department of Microbiology, Immunology and Transplantation, Rega Institute KU Leuven
- Onesphore Majyambere
- National Reference Laboratory, Rwanda Biomedical Center
- Sebastien Bontems
- Department of Clinical Microbiology, University Hospital of Liège
- Bouchra Boujemla
- Laboratory of Human Genetics, GIGA Research Institute
- Josh Quick
- University of Birmingham
- Paola Cristina Resende
- University College London
- Nick Loman
- University of Birmingham
- Esperance Umumararungu
- National Reference Laboratory, Rwanda Biomedical Center
- Alice Kabanda
- National Reference Laboratory, Rwanda Biomedical Center
- Marylin Milumbu Murindahabi
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Patrick Tuyisenge
- National Reference Laboratory, Rwanda Biomedical Center
- Misbah Gashegu
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Jean Paul Rwabihama
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Reuben Sindayiheba
- National Reference Laboratory, Rwanda Biomedical Center
- Djordje Gikic
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Jacob Souopgui
- Center for Human Genetics, College of Medicine and Health Sciences, University of Rwanda
- Wilfred Ndifon
- African Institute for Mathematical Sciences
- Robert Rutayisire
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Swaibu Gatare
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Tharcisse Mpunga
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Daniel Ngamije
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Vincent Bours
- Laboratory of Human Genetics, GIGA Research Institute
- Andrew Rambaut
- Institute of Evolutionary Biology, University of Edinburgh
- Sabin Nsanzimana
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- Guy Baele
- Department of Microbiology, Immunology and Transplantation, Rega Institute KU Leuven
- Keith Durkin
- Laboratory of Human Genetics, GIGA Research Institute
- Leon Mutesa
- Center for Human Genetics, College of Medicine and Health Sciences, University of Rwanda
- Nadine Rujeni
- Rwanda National Joint Task Force COVID-19, Rwanda Biomedical Centre, Ministry of Health
- DOI
- https://doi.org/10.1038/s41467-021-25985-7
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 11
Abstract
Genomic surveillance of SARS-CoV-2 can inform regional transmission dynamics and inform public health interventions. Here, the authors sequence ~200 samples from Rwanda, identify shifts in predominating strains from May 2020 to February 2021, and infer geographic origins.
