Nature Communications (Jan 2017)

Drosophila FIT is a protein-specific satiety hormone essential for feeding control

  • Jinghan Sun,
  • Chang Liu,
  • Xiaobing Bai,
  • Xiaoting Li,
  • Jingyun Li,
  • Zhiping Zhang,
  • Yunpeng Zhang,
  • Jing Guo,
  • Yan Li

DOI
https://doi.org/10.1038/ncomms14161
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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Protein feeding is known to induce strong inhibition on further food intake, though the underlying mechanisms remain poorly understood. Here, the authors identify a protein-specific satiety hormone inDrosophila, and show that it suppresses feeding via promoting DILP2 release in the central nervous system.