Nature Communications (Apr 2020)

Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum

  • Adrià Sogues,
  • Mariano Martinez,
  • Quentin Gaday,
  • Mathilde Ben Assaya,
  • Martin Graña,
  • Alexis Voegele,
  • Michael VanNieuwenhze,
  • Patrick England,
  • Ahmed Haouz,
  • Alexandre Chenal,
  • Sylvain Trépout,
  • Rosario Duran,
  • Anne Marie Wehenkel,
  • Pedro M. Alzari

DOI
https://doi.org/10.1038/s41467-020-15490-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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The mechanisms of Z-ring assembly and regulation in bacteria are poorly understood, particularly in non-model organisms. Here, Sogues et al. study the interaction between FtsZ and SepF in Corynebacterium glutamicum, showing an essential interdependence of these proteins for formation of a functional Z-ring.