Molbank (Dec 2022)
(<i>S</i>,<i>S</i>)-1-(Phenyl((1′-4-nitrophenyl-ethyl)amino)methyl)-2-naphthol
Abstract
The Betti reaction of 2-naphthol, benzaldehyde and (S)-1-(4-nitrophenyl)ethylamine without any solvent gave the corresponding aminobenzylnaphthol, that is the (S,S)-1-(phenyl((1′-4-nitrophenyl-ethyl)amino)methyl)-2-naphthol, in good yield (56%). The absolute configuration of the title compound was attributed by NMR analysis, a procedure that is reliable if compared with the data obtained by X-ray diffraction experiments.
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