Nature Communications (May 2016)

Structural basis for haem piracy from host haemopexin by Haemophilus influenzae

  • Silvia Zambolin,
  • Bernard Clantin,
  • Mohamed Chami,
  • Sylviane Hoos,
  • Ahmed Haouz,
  • Vincent Villeret,
  • Philippe Delepelaire

DOI
https://doi.org/10.1038/ncomms11590
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

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Haemophilus influenzae requires haem, and acquires it from host haemoproteins including haemopexin. Here, the authors examine the haem transport system consisting of HxuA, HxuB and HxuC via the structures of HxuA in complex with haemopexin.