Simulation of the Elastic Interaction between the Probe of Atomic Force Microscope and the Cell

Abstract

The numerical simulation of the interaction between the probe of atomic force microscope and biological cell using finite element contact model was done. The magnitudes of the stress and strain arising during the indentation of the probe into the red blood cells were defined. The cell was considered as a homogeneous elastic body and as hyperelastic body, consisting of the shell and the internal contents. The results of simulation were compared with the analytical solution of the Hertz contact problem.

Keywords

• probe of atomic and force microscope
• cell
• finite element method