Diagnostics (May 2023)

Linear EUS Accuracy in Preoperative Staging of Gastric Cancer: A Retrospective Multicenter Study

  • Germana de Nucci,
  • Tommaso Gabbani,
  • Giovanna Impellizzeri,
  • Simona Deiana,
  • Paolo Biancheri,
  • Laura Ottaviani,
  • Leonardo Frazzoni,
  • Enzo Domenico Mandelli,
  • Paola Soriani,
  • Maurizio Vecchi,
  • Gianpiero Manes,
  • Mauro Manno

DOI
https://doi.org/10.3390/diagnostics13111842
Journal volume & issue
Vol. 13, no. 11
p. 1842

Abstract

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Introduction: Preoperative gastric cancer (GC) staging is the most reliable prognostic factor that affects therapeutic strategies. Contrast-enhanced computed tomography (CECT) and radial endoscopic ultrasound (R-EUS) scans are the most commonly used staging tools for GC. The accuracy of linear EUS (L-EUS) in this setting is still controversial. The aim of this retrospective multicenter study was to evaluate the accuracy of L-EUS and CECT in preoperative GC staging, with regards to depth of tumor invasion (T staging) and nodal involvement (N staging). Materials and methods: 191 consecutive patients who underwent surgical resection for GC were retrospectively enrolled. Preoperative staging had been performed using both L-EUS and CECT, and the results were compared to postoperative staging by histopathologic analysis of surgical specimens. Results: L-EUS diagnostic accuracy for depth of invasion of the GC was 100%, 60%, 74%, and 80% for T1, T2, T3, and T4, respectively. CECT accuracy for T staging was 78%, 55%, 45%, and 10% for T1, T2, T3, and T4, respectively. L-EUS diagnostic accuracy for N staging of GC was 85%, significantly higher than CECT accuracy (61%). Conclusions: Our data suggest that L-EUS has a higher accuracy than CECT in preoperative T and N staging of GC.

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