Insights into Lipid Metabolism and Composition in Parkinson’s Disease Pathogenesis

Abstract

Parkinson’s disease (PD) is a chronic degenerative disorder of the nervous system. Lipids, as fundamental components of cells, are integral to both structural functions and physiological roles. They are essential for the development of brain structures and the maintenance of normal physiological activity in nerve cells. Lipid metabolism is intricately involved in the pathological progression of PD. This review primarily summarizes the abnormalities in lipid metabolism observed in PD, the resultant pathological damage, and lipid metabolism-based therapeutic strategies. Additionally, it discusses recent advancements in related drug research and explores future prospects in this field.

Keywords

• parkinson’s disease
• lipid components
• lipid metabolism
• neurodegenerative diseases