PLoS ONE (Jan 2024)

The relationship between caregiver contribution to self-care and patient quality of life in heart failure: A longitudinal mediation analysis.

  • Gabriele Caggianelli,
  • Fabio Alivernini,
  • Andrea Chirico,
  • Paolo Iovino,
  • Fabio Lucidi,
  • Izabella Uchmanowicz,
  • Laura Rasero,
  • Rosaria Alvaro,
  • Ercole Vellone

DOI
https://doi.org/10.1371/journal.pone.0300101
Journal volume & issue
Vol. 19, no. 3
p. e0300101

Abstract

Read online

BackgroundPatients with heart failure may experience poor quality of life due to a variety of physical and psychological symptoms. Quality of life can improve if patients adhere to consistent self-care behaviors. Patient outcomes (i.e., quality of life) are thought to improve as a result of caregiver contribution to self-care. However, uncertainty exists on whether these outcomes improve as a direct result of caregiver contribution to self-care or whether this improvement occurs indirectly through the improvement of patient heart failure self-care behaviors.AimsTo investigate the influence of caregiver contribution to self-care on quality of life of heart failure people and explore whether patient self-care behaviors mediate such a relationship.MethodsThis is a secondary analysis of the MOTIVATE-HF randomized controlled trial (Clinicaltrials.gov registration number: NCT02894502). Data were collected at baseline and 3 months. An autoregressive longitudinal path analysis model was conducted to test our hypotheses.ResultsWe enrolled a sample of 510 caregivers [mean age = 54 (±15.44), 24% males)] and 510 patients [mean age = 72.4 (±12.28), 58% males)]. Patient self-care had a significant and direct effect on quality of life at three months (β = 0.20, p ConclusionPatient quality of life is influenced by self-care both directly and indirectly, through the mediation of caregiver contribution to self-care. These findings improve our understanding on how caregiver contribution to self-care improves patient outcomes.