Nature Communications (Feb 2016)

Intraoperative intravital microscopy permits the study of human tumour vessels

  • Daniel T. Fisher,
  • Jason B. Muhitch,
  • Minhyung Kim,
  • Kurt C. Doyen,
  • Paul N. Bogner,
  • Sharon S. Evans,
  • Joseph J. Skitzki

DOI
https://doi.org/10.1038/ncomms10684
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 9

Abstract

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Intravital microscopy has been used in laboratory animals to visualise the blood vessels in tumours. Here, the authors use this technique in melanoma patients undergoing surgery and show that vessels in situhave a larger diameter than excised tissue