Frontiers in Psychiatry (Aug 2018)
The Association Between Post-stroke Depression, Aphasia, and Physical Independence in Stroke Patients at 3-Month Follow-Up
- Shuo Wang,
- Shuo Wang,
- Shuo Wang,
- Shuo Wang,
- Shuo Wang,
- Chun-Xue Wang,
- Chun-Xue Wang,
- Chun-Xue Wang,
- Chun-Xue Wang,
- Chun-Xue Wang,
- Chun-Xue Wang,
- Ning Zhang,
- Ning Zhang,
- Ning Zhang,
- Ning Zhang,
- Ning Zhang,
- Yu-Tao Xiang,
- Yang Yang,
- Yang Yang,
- Yang Yang,
- Yang Yang,
- Yang Yang,
- Yu-Zhi Shi,
- Yu-Zhi Shi,
- Yi-Ming Deng,
- Yi-Ming Deng,
- Yi-Ming Deng,
- Mei-Fang Zhu,
- Mei-Fang Zhu,
- Mei-Fang Zhu,
- Mei-Fang Zhu,
- Mei-Fang Zhu,
- Fei Liu,
- Fei Liu,
- Fei Liu,
- Fei Liu,
- Fei Liu,
- Ping Yu,
- Ping Yu,
- Ping Yu,
- Ping Yu,
- Ping Yu,
- Gabor S. Ungvari,
- Chee H. Ng
Affiliations
- Shuo Wang
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Shuo Wang
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Shuo Wang
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Shuo Wang
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Shuo Wang
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Chun-Xue Wang
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Chun-Xue Wang
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Chun-Xue Wang
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Chun-Xue Wang
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Chun-Xue Wang
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Chun-Xue Wang
- Department of Clinical Psychology, Capital Medical University, Beijing, China
- Ning Zhang
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Ning Zhang
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Ning Zhang
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Ning Zhang
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Ning Zhang
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Yu-Tao Xiang
- Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Taipa, Macau
- Yang Yang
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Yang Yang
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Yang Yang
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Yang Yang
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Yang Yang
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Yu-Zhi Shi
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Yu-Zhi Shi
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Yi-Ming Deng
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Yi-Ming Deng
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Yi-Ming Deng
- Department of Interventional Neuroradiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Mei-Fang Zhu
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Mei-Fang Zhu
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Mei-Fang Zhu
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Mei-Fang Zhu
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Mei-Fang Zhu
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Fei Liu
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Fei Liu
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Fei Liu
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Fei Liu
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Fei Liu
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Ping Yu
- Department of Neurology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Ping Yu
- Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China
- Ping Yu
- China National Clinical Research Center for Neurological Diseases, Beijing, China
- Ping Yu
- Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China
- Ping Yu
- Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China
- Gabor S. Ungvari
- University of Notre Dame Australia, Marian Centre and Graylands Hospital, Perth, WA, Australia
- Chee H. Ng
- 0Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia
- DOI
- https://doi.org/10.3389/fpsyt.2018.00374
- Journal volume & issue
-
Vol. 9
Abstract
Objective: Few studies have examined the association between post-stroke depression (PSD), aphasia, and physical independence in Chinese patients. This study investigated the above association in stroke patients in China at 3-month follow-up.Methods: Altogether 270 patients within 14 days after ischemic stroke were recruited and followed up at 3 months. PSD, aphasia, and physical functional status were measured using the Stroke Aphasia Depression Questionnaire (SADQ), Western Aphasia Battery (WAB), and modified Rankin Scale (mRS), respectively. Patients with mRS total score >2 were considered as having “physical dependence.”Results: Out of 248 patients at 3-month follow up, 119 (48%) were rated as having physical dependence. Multiple logistic regression analyses revealed that female (p = 0.04; OR = 2.2; 95% CI: 1.0–5.1), more severe stroke at admission (p < 0.01; OR = 1.4; 95% CI: 1.3–1.5), and more severe PSD at 3 months (p = 0.01; OR = 1.05; 95% CI: 1.01–1.1) were independently associated with physical dependence at 3 months.Conclusions: Greater PSD and stroke severity were independently associated with physical dependence at 3 months after stroke. Aphasia was also associated with physical dependence but the relationship was not significant. Early and effective depression screening, treatment and stroke rehabilitation appear to be important to improve the physical outcome and reduce the burden of stroke survivors.
Keywords
