Global Medical Genetics (Sep 2023)
BL-MOL-AR Project, Preliminary Results about Liquid Biopsy: Molecular Approach Experience and Research Activity in Oncological Settings
- Pancrazzi Pancrazzi,
- Bloise Bloise,
- Moncada Moncada,
- Perticucci Perticucci,
- Vecchietti Vecchietti,
- Pompili Pompili,
- Ricciarini Ricciarini,
- Lenzi Lenzi,
- Gatteschi Gatteschi,
- Giusti Giusti,
- Rosito Rosito,
- Del Buono Del Buono,
- Belardi Belardi,
- Bruni Bruni,
- Borri Borri,
- Campione Campione,
- Laurini Laurini,
- Occhini Occhini,
- Presenti Presenti,
- Viticchi Viticchi,
- Rossi Rossi,
- Bardi Bardi,
- D'Urso D'Urso,
- Dei Dei,
- Venezia Venezia,
- Scala Scala,
- Bengala Bengala,
- Decarli Decarli,
- Carnevali Carnevali,
- Milandri Milandri,
- Ognibene Ognibene
Affiliations
- Pancrazzi Pancrazzi
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Bloise Bloise
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Moncada Moncada
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Perticucci Perticucci
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Vecchietti Vecchietti
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Pompili Pompili
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Ricciarini Ricciarini
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Lenzi Lenzi
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Gatteschi Gatteschi
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- Giusti Giusti
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Rosito Rosito
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Del Buono Del Buono
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Belardi Belardi
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Bruni Bruni
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Borri Borri
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Campione Campione
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Laurini Laurini
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Occhini Occhini
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Presenti Presenti
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Viticchi Viticchi
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Rossi Rossi
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, Misericordia Hospital, Grosseto, Italy
- Bardi Bardi
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, Misericordia Hospital, Grosseto, Italy
- D'Urso D'Urso
- General Management, Local Health Unit South-East Tuscany, Tuscany, Italy
- Dei Dei
- General Management, Local Health Unit South-East Tuscany, Tuscany, Italy
- Venezia Venezia
- Diagnostic Imaging Department, Radiology Unit, San Donato Hospital, Arezzo, Italy
- Scala Scala
- Cardio Thoracic Neuro Vascular Department, Pneumology Unit, San Donato Hospital, Arezzo, Italy
- Bengala Bengala
- Oncology Department, Unit of Medical Oncology, Misericordia Hospital, Grosseto, Italy
- Decarli Decarli
- Oncology Department, Pathological Anatomy Laboratory, Misericordia Hospital, Grosseto, Italy
- Carnevali Carnevali
- Oncology Department, Pathological Anatomy Laboratory, San Donato Hospital, Italy
- Milandri Milandri
- Oncology Department, Unit of Medical Oncology, San Donato Hospital, Arezzo, Italy
- Ognibene Ognibene
- Laboratory Medicine Department, Clinical and Molecular Pathology Sector, San Donato Hospital, Arezzo, Italy
- DOI
- https://doi.org/10.1055/s-0043-1771193
- Journal volume & issue
-
Vol. 10,
no. 03
pp. 172 – 187
Abstract
Background Liquid biopsy is mainly used to identify tumor cells in pulmonary neoplasms. It is more often used in research than in clinical practice. The BL-MOL-AR study aims to investigate the efficacy of next-generation sequencing (NGS) and clinical interpretation of the circulating free DNA (cfDNA) levels. This study reports the preliminary results from the first samples analyzed from patients affected by various neoplasms: lung, intestinal, mammary, gastric, biliary, and cutaneous.
Keywords