Syringocystadenocarcinoma Papilliferum: A case report of a rare skin adnexal tumour

Abstract

Syringocystadenocarcinoma papilliferum (SCACP), a rare skin adnexal carcinoma with apocrine differentiation is the malignant counterpart of syringocystadenoma papilliferum (SCAAP). It usually occurs in the head and neck region of elderly individuals. We describe a 46 year old south Indian female with a lesion in the scalp. Morphologically the tumour had the characteristic features of SCAAP along with frank invasion into deep dermis and malignant cytologic features. Immunohistochemically, the tumour cells stained strongly with cytokeratin (CK) 7, carcinoembryonic antigen (CEA), gross cystic disease fluid protein-15 (GCDFP-15), We made a diagnosis of SCACP in the patient, and a wide excision with skin grafting was performed on the patient.

Keywords

• syringocystadenocarcinoma papilliferum
• adnexal neoplasm
• apocrine differentiation