Nature Communications (Oct 2021)

Hedgehog artificial macrophage with atomic-catalytic centers to combat Drug-resistant bacteria

  • Yanping Long,
  • Ling Li,
  • Tao Xu,
  • Xizheng Wu,
  • Yun Gao,
  • Jianbo Huang,
  • Chao He,
  • Tian Ma,
  • Lang Ma,
  • Chong Cheng,
  • Changsheng Zhao

DOI
https://doi.org/10.1038/s41467-021-26456-9
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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The increase in drug-resistant bacteria is a world-wide health issue that demands the development of alternatives to standard antibiotic treatments. In this study, the authors synthesise a hedgehog artificial macrophage with heme-mimetic catalytic centres, and peroxidase- and haloperoxidase-mimicking activities, for the treatment of methicillin-resistant Staphylococcus aureus.